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Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models

BACKGROUND: Scar and vulnerability models assert that increased psychopathology may predict subsequent executive functioning (EF) deficits (and vice versa) over protracted timescales, yet most prior work on this topic has been cross-sectional. Thus, we tested the within- and between-person relations...

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Autores principales: Zainal, Nur Hani, Newman, Michelle G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278253/
https://www.ncbi.nlm.nih.gov/pubmed/34134796
http://dx.doi.org/10.1192/j.eurpsy.2021.2217
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author Zainal, Nur Hani
Newman, Michelle G.
author_facet Zainal, Nur Hani
Newman, Michelle G.
author_sort Zainal, Nur Hani
collection PubMed
description BACKGROUND: Scar and vulnerability models assert that increased psychopathology may predict subsequent executive functioning (EF) deficits (and vice versa) over protracted timescales, yet most prior work on this topic has been cross-sectional. Thus, we tested the within- and between-person relations between EF, depression, and anxiety. METHODS: Older adult participants (n = 856) were assessed across four waves, approximately 2 years apart. Performance-based EF and caregiver-rated symptom measures were administered. Bivariate latent change score and random-intercept cross-lagged panel models were conducted. RESULTS: Within persons, random-intercept cross-lagged panel models revealed that prior greater depression forecasted lower subsequent EF, and vice versa (d = −0.292 vs. −0.292). Bivariate dual latent change score models showed that within-person rise in depression predicted EF decreases, and vice versa (d = −0.245 vs. −0.245). No within-person, cross-lagged, EF-anxiety relations emerged. Further, significant negative between-person EF-symptom relations were observed (d = −0.264 to −0.395). CONCLUSION: Prospective, within-person findings offer some evidence for developmental scar and vulnerability models.
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spelling pubmed-82782532021-07-20 Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models Zainal, Nur Hani Newman, Michelle G. Eur Psychiatry Research Article BACKGROUND: Scar and vulnerability models assert that increased psychopathology may predict subsequent executive functioning (EF) deficits (and vice versa) over protracted timescales, yet most prior work on this topic has been cross-sectional. Thus, we tested the within- and between-person relations between EF, depression, and anxiety. METHODS: Older adult participants (n = 856) were assessed across four waves, approximately 2 years apart. Performance-based EF and caregiver-rated symptom measures were administered. Bivariate latent change score and random-intercept cross-lagged panel models were conducted. RESULTS: Within persons, random-intercept cross-lagged panel models revealed that prior greater depression forecasted lower subsequent EF, and vice versa (d = −0.292 vs. −0.292). Bivariate dual latent change score models showed that within-person rise in depression predicted EF decreases, and vice versa (d = −0.245 vs. −0.245). No within-person, cross-lagged, EF-anxiety relations emerged. Further, significant negative between-person EF-symptom relations were observed (d = −0.264 to −0.395). CONCLUSION: Prospective, within-person findings offer some evidence for developmental scar and vulnerability models. Cambridge University Press 2021-06-17 /pmc/articles/PMC8278253/ /pubmed/34134796 http://dx.doi.org/10.1192/j.eurpsy.2021.2217 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zainal, Nur Hani
Newman, Michelle G.
Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title_full Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title_fullStr Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title_full_unstemmed Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title_short Depression and executive functioning bidirectionally impair one another across 9 years: Evidence from within-person latent change and cross-lagged models
title_sort depression and executive functioning bidirectionally impair one another across 9 years: evidence from within-person latent change and cross-lagged models
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278253/
https://www.ncbi.nlm.nih.gov/pubmed/34134796
http://dx.doi.org/10.1192/j.eurpsy.2021.2217
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