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Serum Amyloid A1 Induces Classically Activated Macrophages: A Role for Enhanced Fibril Formation

AA amyloidosis belongs to the group of amyloid diseases which can follow chronic inflammatory conditions of various origin. The disease is characterized by the deposition of insoluble amyloid fibrils formed by serum amyloid A1 (SAA1) leading eventually to organ failure. Macrophages are intimately in...

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Detalles Bibliográficos
Autores principales: Gaiser, Ann-Kathrin, Bauer, Shanna, Ruez, Stephanie, Holzmann, Karlheinz, Fändrich, Marcus, Syrovets, Tatiana, Simmet, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278318/
https://www.ncbi.nlm.nih.gov/pubmed/34276683
http://dx.doi.org/10.3389/fimmu.2021.691155

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