Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature

Orthopedic implant-related infections remain a major problem even nowadays. Bacterial resistance through biofilm formation, in addition to the limited treatment options available, has resulted in an increased effort to better understand pathophysiology mechanisms. We performed a review of the litera...

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Detalles Bibliográficos
Autores principales: Rozis, Meletis, Evangelopoulos, Dimitrios S, Pneumaticos, Spyros G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278357/
https://www.ncbi.nlm.nih.gov/pubmed/34306846
http://dx.doi.org/10.7759/cureus.15634
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author Rozis, Meletis
Evangelopoulos, Dimitrios S
Pneumaticos, Spyros G
author_facet Rozis, Meletis
Evangelopoulos, Dimitrios S
Pneumaticos, Spyros G
author_sort Rozis, Meletis
collection PubMed
description Orthopedic implant-related infections remain a major problem even nowadays. Bacterial resistance through biofilm formation, in addition to the limited treatment options available, has resulted in an increased effort to better understand pathophysiology mechanisms. We performed a review of the literature in order to identify major biofilm formation pathways through which possible treatment strategies could arise.
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spelling pubmed-82783572021-07-22 Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature Rozis, Meletis Evangelopoulos, Dimitrios S Pneumaticos, Spyros G Cureus Infectious Disease Orthopedic implant-related infections remain a major problem even nowadays. Bacterial resistance through biofilm formation, in addition to the limited treatment options available, has resulted in an increased effort to better understand pathophysiology mechanisms. We performed a review of the literature in order to identify major biofilm formation pathways through which possible treatment strategies could arise. Cureus 2021-06-14 /pmc/articles/PMC8278357/ /pubmed/34306846 http://dx.doi.org/10.7759/cureus.15634 Text en Copyright © 2021, Rozis et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Rozis, Meletis
Evangelopoulos, Dimitrios S
Pneumaticos, Spyros G
Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title_full Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title_fullStr Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title_full_unstemmed Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title_short Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
title_sort orthopedic implant-related biofilm pathophysiology: a review of the literature
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278357/
https://www.ncbi.nlm.nih.gov/pubmed/34306846
http://dx.doi.org/10.7759/cureus.15634
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