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Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most thermodynamically unstable base pair, the cytosine (C)⋅C mismatch, destabilizes adja...
Autores principales: | Tesfahun, Almaz Nigatu, Alexeeva, Marina, Tomkuvienė, Miglė, Arshad, Aysha, Guragain, Prashanna, Klungland, Arne, Klimašauskas, Saulius, Ruoff, Peter, Bjelland, Svein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278400/ https://www.ncbi.nlm.nih.gov/pubmed/34276575 http://dx.doi.org/10.3389/fmicb.2021.608839 |
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