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PGC-1α attenuates the oxidative stress-induced impaired osteogenesis and angiogenesis regulation effects of mesenchymal stem cells in the presence of diabetic serum

Oxidative stress is believed to induce dysfunction of the bone remodeling process and be associated with progressive loss of bone mass. The peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α) is a master controller during mitochondrial biogenesis and the antioxidant response. We...

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Detalles Bibliográficos
Autores principales: Shi, Zongxin, Wang, Shikun, Deng, Jiechao, Gong, Zishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278528/
https://www.ncbi.nlm.nih.gov/pubmed/34286110
http://dx.doi.org/10.1016/j.bbrep.2021.101070