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Human umbilical cord-derived mesenchymal stem cells improve the function of liver in rats with acute-on-chronic liver failure via downregulating Notch and Stat1/Stat3 signaling

BACKGROUND: Effective treatments for acute-on-chronic liver failure (ACLF) are lacking. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have been applied in tissue regeneration and repair, acting through paracrine effects, cell fusion, and actual transdifferentiation. The present stud...

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Detalles Bibliográficos
Autores principales:	He, Yulin, Guo, Xingrong, Lan, Tingyu, Xia, Jianbo, Wang, Jinsong, Li, Bei, Peng, Chunyan, Chen, Yue, Hu, Xiang, Meng, Zhongji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278604/ https://www.ncbi.nlm.nih.gov/pubmed/34256837 http://dx.doi.org/10.1186/s13287-021-02468-6

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