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Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion

Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and low productivities associated with their production in mam...

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Detalles Bibliográficos
Autores principales: Wang, Yanyan, Li, Xiaowei, Chen, Xin, Nielsen, Jens, Petranovic, Dina, Siewers, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278646/
https://www.ncbi.nlm.nih.gov/pubmed/34261490
http://dx.doi.org/10.1186/s12934-021-01624-0