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Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion
Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and low productivities associated with their production in mam...
Autores principales: | Wang, Yanyan, Li, Xiaowei, Chen, Xin, Nielsen, Jens, Petranovic, Dina, Siewers, Verena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278646/ https://www.ncbi.nlm.nih.gov/pubmed/34261490 http://dx.doi.org/10.1186/s12934-021-01624-0 |
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