Exosomal miR-100-5p inhibits osteogenesis of hBMSCs and angiogenesis of HUVECs by suppressing the BMPR2/Smad1/5/9 signalling pathway

BACKGROUND: Nontraumatic osteonecrosis of the femoral head (NONFH) is a common, progressive, and refractory orthopaedic disease. Decreased osteogenesis and angiogenesis are considered the main factors in the pathogenesis of NONFH. We aimed to figure out whether exosomes and exosomal miRNA from necro...

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Detalles Bibliográficos
Autores principales: Yang, Wu, Zhu, Weiwen, Yang, Yunfei, Guo, Minkang, Qian, Husun, Jiang, Weiqian, Chen, Yu, Lian, Chengjie, Xu, Zijie, Bai, Haobo, Chen, Tingmei, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278698/
https://www.ncbi.nlm.nih.gov/pubmed/34256859
http://dx.doi.org/10.1186/s13287-021-02438-y

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