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Fluoroethylnormemantine, A Novel Derivative of Memantine, Facilitates Extinction Learning Without Sensorimotor Deficits

BACKGROUND: Memantine, a noncompetitive N-methyl-D-aspartate receptor antagonist, has been approved for use in Alzheimer’s disease, but an increasing number of studies have investigated its utility for neuropsychiatric disorders. Here, we characterized a novel compound, fluoroethylnormemtantine (FEN...

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Detalles Bibliográficos
Autores principales: Chen, Briana K, Le Pen, Gwenaëlle, Eckmier, Adam, Rubinstenn, Gilles, Jay, Therese M, Denny, Christine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278800/
https://www.ncbi.nlm.nih.gov/pubmed/33631001
http://dx.doi.org/10.1093/ijnp/pyab007