Chylothorax in a child with rifampicin-resistant tuberculosis

Chylothorax is rare in children. Only a few cases of tuberculosis (TB)-associated chylothorax have been reported. We present a child on standard four-drug TB treatment who presented with wheezing and a chylothorax. Bronchoscopy showed caseating lymph nodes, and rifampicin-resistant TB was identified...

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Detalles Bibliográficos
Autores principales: McLaren, B, Song, X, Mate, E, Jardine, C, Mabaso, T, Mammen, V, Lala, S, Dangor, Z, Verwey, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: South African Medical Association 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278846/
https://www.ncbi.nlm.nih.gov/pubmed/34286258
http://dx.doi.org/10.7196/SARJ.2019.v25i3.237
Descripción
Sumario:Chylothorax is rare in children. Only a few cases of tuberculosis (TB)-associated chylothorax have been reported. We present a child on standard four-drug TB treatment who presented with wheezing and a chylothorax. Bronchoscopy showed caseating lymph nodes, and rifampicin-resistant TB was identified from the bronchoalveolar lavage specimen. There was marked clinical and radiological improvement 1 month after starting multidrug-resistant (MDR) TB treatment and steroids. The association of chylothorax and MDR-TB has not been described in children. MDR-TB should be considered in children who fail adherent, empirically started drug-susceptible TB treatment.

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