Chylothorax in a child with rifampicin-resistant tuberculosis

Chylothorax is rare in children. Only a few cases of tuberculosis (TB)-associated chylothorax have been reported. We present a child on standard four-drug TB treatment who presented with wheezing and a chylothorax. Bronchoscopy showed caseating lymph nodes, and rifampicin-resistant TB was identified...

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Autores principales: McLaren, B, Song, X, Mate, E, Jardine, C, Mabaso, T, Mammen, V, Lala, S, Dangor, Z, Verwey, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: South African Medical Association 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278846/
https://www.ncbi.nlm.nih.gov/pubmed/34286258
http://dx.doi.org/10.7196/SARJ.2019.v25i3.237
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author McLaren, B
Song, X
Mate, E
Jardine, C
Mabaso, T
Mammen, V
Lala, S
Dangor, Z
Verwey, C
author_facet McLaren, B
Song, X
Mate, E
Jardine, C
Mabaso, T
Mammen, V
Lala, S
Dangor, Z
Verwey, C
author_sort McLaren, B
collection PubMed
description Chylothorax is rare in children. Only a few cases of tuberculosis (TB)-associated chylothorax have been reported. We present a child on standard four-drug TB treatment who presented with wheezing and a chylothorax. Bronchoscopy showed caseating lymph nodes, and rifampicin-resistant TB was identified from the bronchoalveolar lavage specimen. There was marked clinical and radiological improvement 1 month after starting multidrug-resistant (MDR) TB treatment and steroids. The association of chylothorax and MDR-TB has not been described in children. MDR-TB should be considered in children who fail adherent, empirically started drug-susceptible TB treatment.
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spelling pubmed-82788462021-07-19 Chylothorax in a child with rifampicin-resistant tuberculosis McLaren, B Song, X Mate, E Jardine, C Mabaso, T Mammen, V Lala, S Dangor, Z Verwey, C Afr J Thorac Crit Care Med Case Report Chylothorax is rare in children. Only a few cases of tuberculosis (TB)-associated chylothorax have been reported. We present a child on standard four-drug TB treatment who presented with wheezing and a chylothorax. Bronchoscopy showed caseating lymph nodes, and rifampicin-resistant TB was identified from the bronchoalveolar lavage specimen. There was marked clinical and radiological improvement 1 month after starting multidrug-resistant (MDR) TB treatment and steroids. The association of chylothorax and MDR-TB has not been described in children. MDR-TB should be considered in children who fail adherent, empirically started drug-susceptible TB treatment. South African Medical Association 2019-09-17 /pmc/articles/PMC8278846/ /pubmed/34286258 http://dx.doi.org/10.7196/SARJ.2019.v25i3.237 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
McLaren, B
Song, X
Mate, E
Jardine, C
Mabaso, T
Mammen, V
Lala, S
Dangor, Z
Verwey, C
Chylothorax in a child with rifampicin-resistant tuberculosis
title Chylothorax in a child with rifampicin-resistant tuberculosis
title_full Chylothorax in a child with rifampicin-resistant tuberculosis
title_fullStr Chylothorax in a child with rifampicin-resistant tuberculosis
title_full_unstemmed Chylothorax in a child with rifampicin-resistant tuberculosis
title_short Chylothorax in a child with rifampicin-resistant tuberculosis
title_sort chylothorax in a child with rifampicin-resistant tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278846/
https://www.ncbi.nlm.nih.gov/pubmed/34286258
http://dx.doi.org/10.7196/SARJ.2019.v25i3.237
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