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Disseminated nocardiosis in an immunocompetent patient

Nocardiosis is a rare opportunistic bacterial infection. We describe an 8-year-old immunocompetent patient who presented with constitutional symptoms suggestive of probable tuberculosis (TB) in whom we confirmed a diagnosis of nocardiosis. Nocardia is a Gram-positive bacterium that is ubiquitous in...

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Autores principales: Ndlovu, M, Jeena, P M, Thula, S A, Singh, S A, Masekela, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: South African Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278857/
https://www.ncbi.nlm.nih.gov/pubmed/34286268
http://dx.doi.org/10.7196/AJTCCM.2019.v25i4.026
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author Ndlovu, M
Jeena, P M
Thula, S A
Singh, S A
Masekela, R
author_facet Ndlovu, M
Jeena, P M
Thula, S A
Singh, S A
Masekela, R
author_sort Ndlovu, M
collection PubMed
description Nocardiosis is a rare opportunistic bacterial infection. We describe an 8-year-old immunocompetent patient who presented with constitutional symptoms suggestive of probable tuberculosis (TB) in whom we confirmed a diagnosis of nocardiosis. Nocardia is a Gram-positive bacterium that is ubiquitous in soil and decaying vegetable matter. N. asteroides is the most common species. Despite the traditional description of nocardiosis as an opportunistic infection, case reports and case series of pulmonary nocardiosis have recently been reported in immunocompetent patients. Three clinical presentations of nocardiosis have been described; acute, subacute and chronic suppurative infections with episodes of exacerbations and remissions. We describe the presentation, diagnosis, management and prognosis of a rare case of disseminated nocardiosis managed initially as disseminated TB with no improvement.
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spelling pubmed-82788572021-07-19 Disseminated nocardiosis in an immunocompetent patient Ndlovu, M Jeena, P M Thula, S A Singh, S A Masekela, R Afr J Thorac Crit Care Med Case Report Nocardiosis is a rare opportunistic bacterial infection. We describe an 8-year-old immunocompetent patient who presented with constitutional symptoms suggestive of probable tuberculosis (TB) in whom we confirmed a diagnosis of nocardiosis. Nocardia is a Gram-positive bacterium that is ubiquitous in soil and decaying vegetable matter. N. asteroides is the most common species. Despite the traditional description of nocardiosis as an opportunistic infection, case reports and case series of pulmonary nocardiosis have recently been reported in immunocompetent patients. Three clinical presentations of nocardiosis have been described; acute, subacute and chronic suppurative infections with episodes of exacerbations and remissions. We describe the presentation, diagnosis, management and prognosis of a rare case of disseminated nocardiosis managed initially as disseminated TB with no improvement. South African Medical Association 2019-12-06 /pmc/articles/PMC8278857/ /pubmed/34286268 http://dx.doi.org/10.7196/AJTCCM.2019.v25i4.026 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ndlovu, M
Jeena, P M
Thula, S A
Singh, S A
Masekela, R
Disseminated nocardiosis in an immunocompetent patient
title Disseminated nocardiosis in an immunocompetent patient
title_full Disseminated nocardiosis in an immunocompetent patient
title_fullStr Disseminated nocardiosis in an immunocompetent patient
title_full_unstemmed Disseminated nocardiosis in an immunocompetent patient
title_short Disseminated nocardiosis in an immunocompetent patient
title_sort disseminated nocardiosis in an immunocompetent patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278857/
https://www.ncbi.nlm.nih.gov/pubmed/34286268
http://dx.doi.org/10.7196/AJTCCM.2019.v25i4.026
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