Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries

DNA encoded libraries (DELs) represent powerful new technology for finding small molecule ligands for proteins and are increasingly being applied to hit finding in medicinal chemistry. Crucial to the synthesis of high quality DELs is the identification of chemical reactions for their assembly that p...

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Detalles Bibliográficos
Autores principales: Hunter, James H., Anderson, Matthew J., Castan, Isaline F. S. F., Graham, Jessica S., Salvini, Catherine L. A., Stanway-Gordon, Harriet A., Crawford, James J., Madin, Andrew, Pairaudeau, Garry, Waring, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278914/
https://www.ncbi.nlm.nih.gov/pubmed/34349922
http://dx.doi.org/10.1039/d1sc03007h

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