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Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019

We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted od...

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Detalles Bibliográficos
Autores principales: Anderson, Blake, Smith, Zirka, Edupuganti, Srilatha, Yan, Xiaobo, Masi, Christopher M, Wu, Henry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279096/
https://www.ncbi.nlm.nih.gov/pubmed/34277887
http://dx.doi.org/10.1093/ofid/ofab315
Descripción
Sumario:We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15–.36]). Our findings support treatment of acute COVID-19 with mAbs.