Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019

We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted od...

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Autores principales: Anderson, Blake, Smith, Zirka, Edupuganti, Srilatha, Yan, Xiaobo, Masi, Christopher M, Wu, Henry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279096/
https://www.ncbi.nlm.nih.gov/pubmed/34277887
http://dx.doi.org/10.1093/ofid/ofab315
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author Anderson, Blake
Smith, Zirka
Edupuganti, Srilatha
Yan, Xiaobo
Masi, Christopher M
Wu, Henry M
author_facet Anderson, Blake
Smith, Zirka
Edupuganti, Srilatha
Yan, Xiaobo
Masi, Christopher M
Wu, Henry M
author_sort Anderson, Blake
collection PubMed
description We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15–.36]). Our findings support treatment of acute COVID-19 with mAbs.
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spelling pubmed-82790962021-07-15 Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019 Anderson, Blake Smith, Zirka Edupuganti, Srilatha Yan, Xiaobo Masi, Christopher M Wu, Henry M Open Forum Infect Dis Brief Reports We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15–.36]). Our findings support treatment of acute COVID-19 with mAbs. Oxford University Press 2021-06-12 /pmc/articles/PMC8279096/ /pubmed/34277887 http://dx.doi.org/10.1093/ofid/ofab315 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Anderson, Blake
Smith, Zirka
Edupuganti, Srilatha
Yan, Xiaobo
Masi, Christopher M
Wu, Henry M
Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title_full Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title_fullStr Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title_full_unstemmed Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title_short Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
title_sort effect of monoclonal antibody treatment on clinical outcomes in ambulatory patients with coronavirus disease 2019
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279096/
https://www.ncbi.nlm.nih.gov/pubmed/34277887
http://dx.doi.org/10.1093/ofid/ofab315
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