Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development

Inflammation is an essential mechanism of various diseases. The development and resolution of inflammation are complex immune-modulation processes which induce the involvement of various types of immune cells. Specialized pro-resolving lipid mediators (SPMs) have been demonstrated to be signaling mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ailin, Wu, Yanjun, Yu, Ganggang, Wang, Haoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279385/
https://www.ncbi.nlm.nih.gov/pubmed/34261470
http://dx.doi.org/10.1186/s12931-021-01792-y
_version_ 1783722445802307584
author Yang, Ailin
Wu, Yanjun
Yu, Ganggang
Wang, Haoyan
author_facet Yang, Ailin
Wu, Yanjun
Yu, Ganggang
Wang, Haoyan
author_sort Yang, Ailin
collection PubMed
description Inflammation is an essential mechanism of various diseases. The development and resolution of inflammation are complex immune-modulation processes which induce the involvement of various types of immune cells. Specialized pro-resolving lipid mediators (SPMs) have been demonstrated to be signaling molecules in inflammation. SPMs are involved in the pathophysiology of different diseases, especially respiratory diseases, including asthma, pneumonia, and chronic obstructive pulmonary disease. All of these diseases are related to the inflammatory response and its persistence. Therefore, a deeper understanding of the mechanisms and development of inflammation in respiratory disease, and the roles of the SPM family in the resolution process, might be useful in the quest for novel therapies and preventive measures for pulmonary diseases.
format Online
Article
Text
id pubmed-8279385
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-82793852021-07-16 Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development Yang, Ailin Wu, Yanjun Yu, Ganggang Wang, Haoyan Respir Res Review Inflammation is an essential mechanism of various diseases. The development and resolution of inflammation are complex immune-modulation processes which induce the involvement of various types of immune cells. Specialized pro-resolving lipid mediators (SPMs) have been demonstrated to be signaling molecules in inflammation. SPMs are involved in the pathophysiology of different diseases, especially respiratory diseases, including asthma, pneumonia, and chronic obstructive pulmonary disease. All of these diseases are related to the inflammatory response and its persistence. Therefore, a deeper understanding of the mechanisms and development of inflammation in respiratory disease, and the roles of the SPM family in the resolution process, might be useful in the quest for novel therapies and preventive measures for pulmonary diseases. BioMed Central 2021-07-14 2021 /pmc/articles/PMC8279385/ /pubmed/34261470 http://dx.doi.org/10.1186/s12931-021-01792-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Yang, Ailin
Wu, Yanjun
Yu, Ganggang
Wang, Haoyan
Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title_full Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title_fullStr Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title_full_unstemmed Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title_short Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
title_sort role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279385/
https://www.ncbi.nlm.nih.gov/pubmed/34261470
http://dx.doi.org/10.1186/s12931-021-01792-y
work_keys_str_mv AT yangailin roleofspecializedproresolvinglipidmediatorsinpulmonaryinflammationdiseasesmechanismsanddevelopment
AT wuyanjun roleofspecializedproresolvinglipidmediatorsinpulmonaryinflammationdiseasesmechanismsanddevelopment
AT yuganggang roleofspecializedproresolvinglipidmediatorsinpulmonaryinflammationdiseasesmechanismsanddevelopment
AT wanghaoyan roleofspecializedproresolvinglipidmediatorsinpulmonaryinflammationdiseasesmechanismsanddevelopment

Ejemplares similares