Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand

[Image: see text] Over recent years, αvβ6 and αvβ8 Arg-Gly-Asp (RGD) integrins have risen to prominence as interchangeable co-receptors for the cellular entry of herpes simplex virus-1 (HSV-1). In fact, the employment of subtype-specific integrin-neutralizing antibodies or gene-silencing siRNAs has...

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Detalles Bibliográficos
Autores principales: Tomassi, Stefano, D’Amore, Vincenzo Maria, Di Leva, Francesco Saverio, Vannini, Andrea, Quilici, Giacomo, Weinmüller, Michael, Reichart, Florian, Amato, Jussara, Romano, Barbara, Izzo, Angelo Antonio, Di Maro, Salvatore, Novellino, Ettore, Musco, Giovanna, Gianni, Tatiana, Kessler, Horst, Marinelli, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279406/
https://www.ncbi.nlm.nih.gov/pubmed/33961417
http://dx.doi.org/10.1021/acs.jmedchem.1c00533

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