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Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective

[Image: see text] Since their discovery as distinct receptor proteins, the specific physiopathological role of sigma receptors (σRs) has been deeply investigated. It has been reported that these proteins, classified into two subtypes indicated as σ(1) and σ(2), might play a pivotal role in cancer gr...

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Detalles Bibliográficos
Autores principales: Fallica, Antonino N., Pittalà, Valeria, Modica, Maria N., Salerno, Loredana, Romeo, Giuseppe, Marrazzo, Agostino, Helal, Mohamed A., Intagliata, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279423/
https://www.ncbi.nlm.nih.gov/pubmed/34076441
http://dx.doi.org/10.1021/acs.jmedchem.0c02265

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