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Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective
[Image: see text] Since their discovery as distinct receptor proteins, the specific physiopathological role of sigma receptors (σRs) has been deeply investigated. It has been reported that these proteins, classified into two subtypes indicated as σ(1) and σ(2), might play a pivotal role in cancer gr...
Autores principales: | Fallica, Antonino N., Pittalà, Valeria, Modica, Maria N., Salerno, Loredana, Romeo, Giuseppe, Marrazzo, Agostino, Helal, Mohamed A., Intagliata, Sebastiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279423/ https://www.ncbi.nlm.nih.gov/pubmed/34076441 http://dx.doi.org/10.1021/acs.jmedchem.0c02265 |
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