Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A(4) Mimetics (QNX-sLXms)

[Image: see text] Failure to resolve inflammation underlies many prevalent pathologies. Recent insights have identified lipid mediators, typified by lipoxins (LXs), as drivers of inflammation resolution, suggesting potential therapeutic benefit. We report the asymmetric preparation of novel quinoxal...

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Detalles Bibliográficos
Autores principales: de Gaetano, Monica, Tighe, Catherine, Gahan, Kevin, Zanetti, Andrea, Chen, Jianmin, Newson, Justine, Cacace, Antonino, Marai, Mariam, Gaffney, Andrew, Brennan, Eoin, Kantharidis, Phillip, Cooper, Mark E., Leroy, Xavier, Perretti, Mauro, Gilroy, Derek, Godson, Catherine, Guiry, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279484/
https://www.ncbi.nlm.nih.gov/pubmed/34138563
http://dx.doi.org/10.1021/acs.jmedchem.1c00403

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