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Protein–Ligand Binding Volume Determined from a Single 2D NMR Spectrum with Increasing Pressure

[Image: see text] Proteins undergo changes in their partial volumes in numerous biological processes such as enzymatic catalysis, unfolding–refolding, and ligand binding. The change in the protein volume upon ligand binding—a parameter termed the protein–ligand binding volume—can be extensively stud...

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Detalles Bibliográficos
Autores principales: Skvarnavičius, Gediminas, Toleikis, Zigmantas, Michailovienė, Vilma, Roumestand, Christian, Matulis, Daumantas, Petrauskas, Vytautas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279561/
https://www.ncbi.nlm.nih.gov/pubmed/34032445
http://dx.doi.org/10.1021/acs.jpcb.1c02917