Heparin impairs skeletal muscle glucose uptake by inhibiting insulin binding to insulin receptor

AIM: Heparin, a widely used antithrombotic drug has many other anticoagulant‐independent physiological functions. Here, we elucidate a novel role of heparin in glucose homeostasis, suggesting an approach for developing heparin‐targeted therapies for diabetes. METHODS: For serum heparin levels and co...

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Detalles Bibliográficos
Autores principales: Zhu, Canjun, Xu, Zhiyue, Yuan, Yexian, Wang, Tao, Xu, Chang, Yin, Cong, Xie, Peipei, Xu, Pingwen, Ye, Hui, Patel, Nirali, Schaul, Sarah, Wang, Lina, Zhu, Xiaotong, Wang, Songbo, Gao, Ping, Xi, Qianyun, Zhang, Yongliang, Shu, Gang, Jiang, Qingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279624/
https://www.ncbi.nlm.nih.gov/pubmed/34277977
http://dx.doi.org/10.1002/edm2.253

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