Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

Tuberous sclerosis complex (TSC) is a genetic disorder that is associated with multiple neurological manifestations. Previously, we demonstrated that Tsc1 loss in cerebellar Purkinje cells (PCs) can cause altered social behavior in mice. Here, we performed detailed transcriptional and translational...

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Detalles Bibliográficos
Autores principales: Dalal, Jasbir Singh, Winden, Kellen Diamond, Salussolia, Catherine Lourdes, Sundberg, Maria, Singh, Achint, Pham, Truc Thanh, Zhou, Pingzhu, Pu, William T, Miller, Meghan T, Sahin, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279760/
https://www.ncbi.nlm.nih.gov/pubmed/34259631
http://dx.doi.org/10.7554/eLife.67399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279760/
https://www.ncbi.nlm.nih.gov/pubmed/34259631
http://dx.doi.org/10.7554/eLife.67399

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