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Pink1/PARK2/mROS-Dependent Mitophagy Initiates the Sensitization of Cancer Cells to Radiation

Autophagy plays a double-edged sword for cancer; particularly, mitophagy plays important roles in the selective degradation of damaged mitochondria. However, whether mitophagy is involved in killing effects of tumor cells by ionizing radiation (IR) and its underlying mechanism remain elusive. The pu...

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Detalles Bibliográficos
Autores principales:	Yu, Lei, Yang, Xiangshan, Li, Xin, Qin, Lijing, Xu, Weiqiang, Cui, Hongli, Jia, Zhen, He, Qiang, Wang, Zhicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279859/ https://www.ncbi.nlm.nih.gov/pubmed/34306311 http://dx.doi.org/10.1155/2021/5595652

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