Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare

An outbreak of Klebsiella pneumoniae producing the carbapenemase NDM-1 occurred in our ICU during the last COVID-19 wave. Twelve patients were tested positive, seven remained asymptomatic whereas 5 developed an infection. Resistome and in silico multilocus sequence typing confirmed the clonal origin...

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Autores principales: Amarsy, Rishma, Jacquier, Hervé, Munier, Anne-Lise, Merimèche, Manel, Berçot, Béatrice, Mégarbane, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279923/
https://www.ncbi.nlm.nih.gov/pubmed/34273465
http://dx.doi.org/10.1016/j.ajic.2021.07.004
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author Amarsy, Rishma
Jacquier, Hervé
Munier, Anne-Lise
Merimèche, Manel
Berçot, Béatrice
Mégarbane, Bruno
author_facet Amarsy, Rishma
Jacquier, Hervé
Munier, Anne-Lise
Merimèche, Manel
Berçot, Béatrice
Mégarbane, Bruno
author_sort Amarsy, Rishma
collection PubMed
description An outbreak of Klebsiella pneumoniae producing the carbapenemase NDM-1 occurred in our ICU during the last COVID-19 wave. Twelve patients were tested positive, seven remained asymptomatic whereas 5 developed an infection. Resistome and in silico multilocus sequence typing confirmed the clonal origin of the strains. The identification of a possible environmental reservoir suggested that difficulties in observing optimal bio-cleaning procedures due to workload and exhaustion contributed to the outbreak besides the inappropriate excessive glove use.
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spelling pubmed-82799232021-07-20 Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare Amarsy, Rishma Jacquier, Hervé Munier, Anne-Lise Merimèche, Manel Berçot, Béatrice Mégarbane, Bruno Am J Infect Control Brief Report An outbreak of Klebsiella pneumoniae producing the carbapenemase NDM-1 occurred in our ICU during the last COVID-19 wave. Twelve patients were tested positive, seven remained asymptomatic whereas 5 developed an infection. Resistome and in silico multilocus sequence typing confirmed the clonal origin of the strains. The identification of a possible environmental reservoir suggested that difficulties in observing optimal bio-cleaning procedures due to workload and exhaustion contributed to the outbreak besides the inappropriate excessive glove use. Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021-10 2021-07-15 /pmc/articles/PMC8279923/ /pubmed/34273465 http://dx.doi.org/10.1016/j.ajic.2021.07.004 Text en © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Amarsy, Rishma
Jacquier, Hervé
Munier, Anne-Lise
Merimèche, Manel
Berçot, Béatrice
Mégarbane, Bruno
Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title_full Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title_fullStr Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title_full_unstemmed Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title_short Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
title_sort outbreak of ndm-1-producing klebsiella pneumoniae in the intensive care unit during the covid-19 pandemic: another nightmare
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279923/
https://www.ncbi.nlm.nih.gov/pubmed/34273465
http://dx.doi.org/10.1016/j.ajic.2021.07.004
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