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Does positive MGMT methylation outbalance the limitation of subtotal resection in glioblastoma IDH-wildtype patients?

BACKGROUND: The impact on survival of complete resection (CR) in patients with malignant glioma and MGMT promoter methylation on adjuvant therapy strategies has been proven in the past. However, it is not known whether a MGMT promoter methylation can compensate a subtotal resection. Therefore, we an...

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Detalles Bibliográficos
Autores principales: Mareike, Müller, Franziska, Staub-Bartelt, Julia, Ehrmann, Daniel, Hänggi, Michael, Sabel, Jörg, Felsberg, Marion, Rapp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279995/
https://www.ncbi.nlm.nih.gov/pubmed/34185258
http://dx.doi.org/10.1007/s11060-021-03794-8