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DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism

Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer with limited treatment options. Cisplatin (DDP) is used as a mainstay of chemotherapeutic agents in combination with other drugs or radiotherapy for PDAC therapy. However, DDP exhibits severe side-effects that can lead to disconti...

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Detalles Bibliográficos
Autores principales:	Du, Jing, Wang, Xu, Li, Yanchun, Ren, Xueying, Zhou, Yi, Hu, Wanye, Zhou, Chaoting, Jing, Qiangan, Yang, Chen, Wang, Luyang, Li, Huanjuan, Fang, Lijuan, Zhou, Yonglie, Tong, Xiangmin, Wang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280115/ https://www.ncbi.nlm.nih.gov/pubmed/34262021 http://dx.doi.org/10.1038/s41419-021-03996-y

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