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Disorder predispositions and protections of Labrador Retrievers in the UK

The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common diso...

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Autores principales: Pegram, Camilla, Woolley, Charlotte, Brodbelt, Dave C., Church, David B., O’Neill, Dan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280121/
https://www.ncbi.nlm.nih.gov/pubmed/34262062
http://dx.doi.org/10.1038/s41598-021-93379-2
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author Pegram, Camilla
Woolley, Charlotte
Brodbelt, Dave C.
Church, David B.
O’Neill, Dan G.
author_facet Pegram, Camilla
Woolley, Charlotte
Brodbelt, Dave C.
Church, David B.
O’Neill, Dan G.
author_sort Pegram, Camilla
collection PubMed
description The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common disorders in the Labrador Retriever. The clinical records of a random sample of dogs were reviewed to extract the most definitive diagnoses for all disorders recorded during 2016. A list of disorders was generated, including the 30 most common disorders in Labrador Retrievers and the 30 most common disorders in non-Labrador Retrievers. Multivariable logistic regression was used to report the odds of each of these disorders in 1462 (6.6%) Labrador Retrievers compared with 20,786 (93.4%) non-Labrador Retrievers. At a specific-level of diagnostic precision, after accounting for confounding, Labrador Retrievers had significantly increased odds of 12/35 (34.3%) disorders compared to non-Labrador Retrievers; osteoarthritis (OR 2.83) had the highest odds. Conversely, Labrador Retrievers had reduced odds of 7/35 (20.0%) disorders; patellar luxation (OR 0.18) had the lowest odds. This study provides useful information about breed-specific disorder predispositions and protections, which future research could evaluate further to produce definitive guidance for Labrador Retriever breeders and owners.
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spelling pubmed-82801212021-07-15 Disorder predispositions and protections of Labrador Retrievers in the UK Pegram, Camilla Woolley, Charlotte Brodbelt, Dave C. Church, David B. O’Neill, Dan G. Sci Rep Article The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common disorders in the Labrador Retriever. The clinical records of a random sample of dogs were reviewed to extract the most definitive diagnoses for all disorders recorded during 2016. A list of disorders was generated, including the 30 most common disorders in Labrador Retrievers and the 30 most common disorders in non-Labrador Retrievers. Multivariable logistic regression was used to report the odds of each of these disorders in 1462 (6.6%) Labrador Retrievers compared with 20,786 (93.4%) non-Labrador Retrievers. At a specific-level of diagnostic precision, after accounting for confounding, Labrador Retrievers had significantly increased odds of 12/35 (34.3%) disorders compared to non-Labrador Retrievers; osteoarthritis (OR 2.83) had the highest odds. Conversely, Labrador Retrievers had reduced odds of 7/35 (20.0%) disorders; patellar luxation (OR 0.18) had the lowest odds. This study provides useful information about breed-specific disorder predispositions and protections, which future research could evaluate further to produce definitive guidance for Labrador Retriever breeders and owners. Nature Publishing Group UK 2021-07-14 /pmc/articles/PMC8280121/ /pubmed/34262062 http://dx.doi.org/10.1038/s41598-021-93379-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pegram, Camilla
Woolley, Charlotte
Brodbelt, Dave C.
Church, David B.
O’Neill, Dan G.
Disorder predispositions and protections of Labrador Retrievers in the UK
title Disorder predispositions and protections of Labrador Retrievers in the UK
title_full Disorder predispositions and protections of Labrador Retrievers in the UK
title_fullStr Disorder predispositions and protections of Labrador Retrievers in the UK
title_full_unstemmed Disorder predispositions and protections of Labrador Retrievers in the UK
title_short Disorder predispositions and protections of Labrador Retrievers in the UK
title_sort disorder predispositions and protections of labrador retrievers in the uk
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280121/
https://www.ncbi.nlm.nih.gov/pubmed/34262062
http://dx.doi.org/10.1038/s41598-021-93379-2
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