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Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins
Symmetry establishment is a critical process in the development of multicellular organs and requires careful coordination of polarity axes while cells actively divide within tissues. Formation of the apical style in the Arabidopsis gynoecium involves a bilateral-to-radial symmetry transition, a step...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280177/ https://www.ncbi.nlm.nih.gov/pubmed/34262040 http://dx.doi.org/10.1038/s41467-021-24550-6 |
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author | Carabelli, Monica Turchi, Luana Morelli, Giorgio Østergaard, Lars Ruberti, Ida Moubayidin, Laila |
author_facet | Carabelli, Monica Turchi, Luana Morelli, Giorgio Østergaard, Lars Ruberti, Ida Moubayidin, Laila |
author_sort | Carabelli, Monica |
collection | PubMed |
description | Symmetry establishment is a critical process in the development of multicellular organs and requires careful coordination of polarity axes while cells actively divide within tissues. Formation of the apical style in the Arabidopsis gynoecium involves a bilateral-to-radial symmetry transition, a stepwise process underpinned by the dynamic distribution of the plant morphogen auxin. Here we show that SPATULA (SPT) and the HECATE (HEC) bHLH proteins mediate the final step in the style radialisation process and synergistically control the expression of adaxial-identity genes, HOMEOBOX ARABIDOPSIS THALIANA 3 (HAT3) and ARABIDOPSIS THALIANA HOMEOBOX 4 (ATHB4). HAT3/ATHB4 module drives radialisation of the apical style by promoting basal-to-apical auxin flow and via a negative feedback mechanism that finetune auxin distribution through repression of SPT expression and cytokinin sensitivity. Thus, this work reveals the molecular basis of axes-coordination and hormonal cross-talk during the sequential steps of symmetry transition in the Arabidopsis style. |
format | Online Article Text |
id | pubmed-8280177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-82801772021-07-23 Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins Carabelli, Monica Turchi, Luana Morelli, Giorgio Østergaard, Lars Ruberti, Ida Moubayidin, Laila Nat Commun Article Symmetry establishment is a critical process in the development of multicellular organs and requires careful coordination of polarity axes while cells actively divide within tissues. Formation of the apical style in the Arabidopsis gynoecium involves a bilateral-to-radial symmetry transition, a stepwise process underpinned by the dynamic distribution of the plant morphogen auxin. Here we show that SPATULA (SPT) and the HECATE (HEC) bHLH proteins mediate the final step in the style radialisation process and synergistically control the expression of adaxial-identity genes, HOMEOBOX ARABIDOPSIS THALIANA 3 (HAT3) and ARABIDOPSIS THALIANA HOMEOBOX 4 (ATHB4). HAT3/ATHB4 module drives radialisation of the apical style by promoting basal-to-apical auxin flow and via a negative feedback mechanism that finetune auxin distribution through repression of SPT expression and cytokinin sensitivity. Thus, this work reveals the molecular basis of axes-coordination and hormonal cross-talk during the sequential steps of symmetry transition in the Arabidopsis style. Nature Publishing Group UK 2021-07-14 /pmc/articles/PMC8280177/ /pubmed/34262040 http://dx.doi.org/10.1038/s41467-021-24550-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Carabelli, Monica Turchi, Luana Morelli, Giorgio Østergaard, Lars Ruberti, Ida Moubayidin, Laila Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title | Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title_full | Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title_fullStr | Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title_full_unstemmed | Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title_short | Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins |
title_sort | coordination of biradial-to-radial symmetry and tissue polarity by hd-zip ii proteins |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280177/ https://www.ncbi.nlm.nih.gov/pubmed/34262040 http://dx.doi.org/10.1038/s41467-021-24550-6 |
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