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Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells
Molecular single cell analyses provide insights into physiological and pathological processes. Here, in a stepwise approach, we first evaluate 19 protocols for single cell small RNA sequencing on MCF7 cells spiked with 1 pg of 1,006 miRNAs. Second, we analyze MCF7 single cell equivalents of the eigh...
Autores principales: | Hücker, Sarah M., Fehlmann, Tobias, Werno, Christian, Weidele, Kathrin, Lüke, Florian, Schlenska-Lange, Anke, Klein, Christoph A., Keller, Andreas, Kirsch, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280203/ https://www.ncbi.nlm.nih.gov/pubmed/34262050 http://dx.doi.org/10.1038/s41467-021-24611-w |
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