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CKD-506: A novel HDAC6-selective inhibitor that exerts therapeutic effects in a rodent model of multiple sclerosis
Despite advances in therapeutic strategies for multiple sclerosis (MS), the therapy options remain limited with various adverse effects. Here, the therapeutic potential of CKD-506, a novel HDAC6-selective inhibitor, against MS was evaluated in mice with myelin oligodendrocyte glycoprotein(35–55) (MO...
Autores principales: | Bae, Daekwon, Lee, Ji-Young, Ha, Nina, Park, Jinsol, Baek, Jiyeon, Suh, Donghyeon, Lim, Hee Seon, Ko, Soo Min, Kim, Taehee, Som Jeong, Da, Son, Woo-chan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280216/ https://www.ncbi.nlm.nih.gov/pubmed/34262061 http://dx.doi.org/10.1038/s41598-021-93232-6 |
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