Cargando…
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion. In this study, we identify v-maf musculoaponeurotic fibr...
Autores principales: | Moon, Eui Jung, Mello, Stephano S., Li, Caiyun G., Chi, Jen-Tsan, Thakkar, Kaushik, Kirkland, Jacob G., Lagory, Edward L., Lee, Ik Jae, Diep, Anh N., Miao, Yu, Rafat, Marjan, Vilalta, Marta, Castellini, Laura, Krieg, Adam J., Graves, Edward E., Attardi, Laura D., Giaccia, Amato J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280233/ https://www.ncbi.nlm.nih.gov/pubmed/34262028 http://dx.doi.org/10.1038/s41467-021-24631-6 |
Ejemplares similares
-
A low-carb diet kills tumor cells with a mutant p53 tumor suppressor gene: The Atkins diet suppresses tumor growth
por: LaGory, Edward L., et al.
Publicado: (2013) -
Tumor immunologic heterogeneity influences response to radiation and combination immunotherapy
por: Aguilera, Todd, et al.
Publicado: (2015) -
KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage
por: Castellini, Laura, et al.
Publicado: (2017) -
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma
por: Klasson, Timothy D., et al.
Publicado: (2022) -
HIF‐2: The Missing Link Between Obesity and Cardiomyopathy
por: Giaccia, Amato J.
Publicado: (2013)