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Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions

Ketamine has been in use for over 50 years as a general anesthetic, acting primarily through blockade of N-methyl-D-aspartate receptors in the brain. Recent studies have demonstrated that ketamine also acts as a potent and rapid-acting antidepressant when administered at sub-anesthetic doses. Howeve...

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Detalles Bibliográficos
Autores principales:	Geiger, Zachary, VanVeller, Brett, Lopez, Zarin, Harrata, Abdel K., Battani, Kathryn, Wegman-Points, Lauren, Yuan, Li-Lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280316/ https://www.ncbi.nlm.nih.gov/pubmed/34276289 http://dx.doi.org/10.3389/fnins.2021.678978

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