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Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation
Selenoprotein P (SELENOP1) is a selenium-rich antioxidant protein involved in extracellular transport of selenium (Se). SELENOP1 also has metal binding properties. The trace element Zinc (Zn(2+)) is a neuromodulator that can be released from synaptic terminals in the brain, primarily from a subset o...
Autores principales: | Kiyohara, Arlene C. P., Torres, Daniel J., Hagiwara, Ayaka, Pak, Jenna, Rueli, Rachel H. L. H., Shuttleworth, C. William R., Bellinger, Frederick P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280497/ https://www.ncbi.nlm.nih.gov/pubmed/34277682 http://dx.doi.org/10.3389/fnut.2021.683154 |
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