Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment

Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on...

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Detalles Bibliográficos
Autores principales: Wong, Tiffany H., Ambinder, David, Flusberg, Milana, Shakil, Fouzia, Phillips, John L., Wong, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280511/
https://www.ncbi.nlm.nih.gov/pubmed/34285882
http://dx.doi.org/10.1016/j.eucr.2021.101775
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author Wong, Tiffany H.
Ambinder, David
Flusberg, Milana
Shakil, Fouzia
Phillips, John L.
Wong, Nathan C.
author_facet Wong, Tiffany H.
Ambinder, David
Flusberg, Milana
Shakil, Fouzia
Phillips, John L.
Wong, Nathan C.
author_sort Wong, Tiffany H.
collection PubMed
description Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.
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spelling pubmed-82805112021-07-19 Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment Wong, Tiffany H. Ambinder, David Flusberg, Milana Shakil, Fouzia Phillips, John L. Wong, Nathan C. Urol Case Rep Oncology Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI. Elsevier 2021-07-09 /pmc/articles/PMC8280511/ /pubmed/34285882 http://dx.doi.org/10.1016/j.eucr.2021.101775 Text en © 2021 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Wong, Tiffany H.
Ambinder, David
Flusberg, Milana
Shakil, Fouzia
Phillips, John L.
Wong, Nathan C.
Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title_full Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title_fullStr Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title_full_unstemmed Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title_short Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
title_sort small lymphocytic lymphoma of the prostate mimicking a pirads 5 lesion that resolved after systemic treatment
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280511/
https://www.ncbi.nlm.nih.gov/pubmed/34285882
http://dx.doi.org/10.1016/j.eucr.2021.101775
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