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Personalized Proteome: Comparing Proteogenomics and Open Variant Search Approaches for Single Amino Acid Variant Detection
[Image: see text] Discovery of variant peptides such as a single amino acid variant (SAAV) in shotgun proteomics data is essential for personalized proteomics. Both the resolution of shotgun proteomics methods and the search engines have improved dramatically, allowing for confident identification o...
Autores principales: | Salz, Renee, Bouwmeester, Robbin, Gabriels, Ralf, Degroeve, Sven, Martens, Lennart, Volders, Pieter-Jan, ’t Hoen, Peter A.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280751/ https://www.ncbi.nlm.nih.gov/pubmed/33998808 http://dx.doi.org/10.1021/acs.jproteome.1c00264 |
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