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Imidazolium labelling permits the sensitive mass-spectrometric detection of N-glycosides directly from serum
A novel imidazolium derivative (GITag) shows superior ionisation and consequently allows increased mass spectrometric detection capabilities of oligosaccharides and N-glycans. Here we demonstrate that human serum samples can be directly labelled by GITag on a MALDI target plate, abrogating prevalent...
Autores principales: | Zhang, Yao-Yao, Ghirardello, Mattia, Wang, Ting, Lu, Ai-Min, Liu, Li, Voglmeir, Josef, Galan, M. Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280963/ https://www.ncbi.nlm.nih.gov/pubmed/34159978 http://dx.doi.org/10.1039/d1cc02100a |
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