Cargando…

BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke

Microglial phagocytosis benefits neurological recovery after stroke. Large-conductance Ca2(+)-activated K(+) currents are expressed in activated microglia, and BK channel knockout aggravates cerebral ischemic injury. However, the effect of BK channels on microglial phagocytosis after ischemic stroke...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Shuxian, Chen, Tingting, Suo, Qian, Shi, Rubing, Khan, Haroon, Ma, Yuanyuan, Tang, Yaohui, Yang, Guo-Yuan, Zhang, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281043/ https://www.ncbi.nlm.nih.gov/pubmed/34276309 http://dx.doi.org/10.3389/fncel.2021.683769

Ejemplares similares

Erythropoietin Enhances Post-ischemic Migration and Phagocytosis and Alleviates the Activation of Inflammasomes in Human Microglial Cells
por: Arik, Eren, et al.
Publicado: (2022)

The Role of Microglial Phagocytosis in Ischemic Stroke
por: Jia, Junqiu, et al.
Publicado: (2022)

The P2X(7) Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis
por: Campagno, Keith E., et al.
Publicado: (2021)

BK(Ca) channel dysfunction in neurological diseases
por: N'Gouemo, Prosper
Publicado: (2014)

Pertussis Toxin Ameliorates Microglial Activation Associated With Ischemic Stroke
por: Zhou, Feihui, et al.
Publicado: (2020)

Dysregulated Microglial Cell Activation and Proliferation Following Repeated Antigen Stimulation
por: Prasad, Sujata, et al.
Publicado: (2021)

Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis
por: Guan, Zhangxin, et al.
Publicado: (2020)

Reticulocalbin-1 Facilitates Microglial Phagocytosis
por: Ding, Ying, et al.
Publicado: (2015)

M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice
por: Li, Zongwei, et al.
Publicado: (2021)

Effects of Exosomes on Neurological Function Recovery for Ischemic Stroke in Pre-clinical Studies: A Meta-analysis
por: Huang, Mudan, et al.
Publicado: (2020)

Nitric oxide decreases the excitability of interstitial cells of Cajal through activation of the BK channel
por: Zhu, Yaohui, et al.
Publicado: (2008)

Pharmacological Targeting of CSF1R Inhibits Microglial Proliferation and Aggravates the Progression of Cerebral Ischemic Pathology
por: Hou, Boru, et al.
Publicado: (2020)

Qki is an essential regulator of microglial phagocytosis in demyelination
por: Ren, Jiangong, et al.
Publicado: (2020)

Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury
por: Du, Hao, et al.
Publicado: (2022)

Regulation of microglia phagocytosis and potential involvement of exercise
por: Li, Congqin, et al.
Publicado: (2022)

P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis
por: Wen, Ruo‐Xue, et al.
Publicado: (2020)

BK polyomavirus: latency, reactivation, diseases and tumorigenesis
por: Zhou, Xianfeng, et al.
Publicado: (2023)

Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway
por: Ke, Hongfei, et al.
Publicado: (2020)

Dose-Dependent Microglial and Astrocytic Responses Associated With Post-ischemic Neuroprotection After Lipopolysaccharide-Induced Sepsis-Like State in Mice
por: Sardari, Maryam, et al.
Publicado: (2020)

Roles of peripheral immune cells in the recovery of neurological function after ischemic stroke
por: Zhang, Zhaolong, et al.
Publicado: (2022)

Microglial Immunometabolism in Alzheimer’s Disease
por: Shippy, Daniel C., et al.
Publicado: (2020)

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
por: Konishi, Hiroyuki, et al.
Publicado: (2020)

Interrogation of human microglial phagocytosis by CRISPR genome editing
por: Chang, Jason Cheng-Yu, et al.
Publicado: (2023)

Mitochondrial BK(Ca) channel
por: Balderas, Enrique, et al.
Publicado: (2015)

Hydrophobic gating in BK channels
por: Jia, Zhiguang, et al.
Publicado: (2018)

Enhancement Effects of Martentoxin on Glioma BK Channel and BK Channel (α+β1) Subtypes
por: Tao, Jie, et al.
Publicado: (2011)

Increasing brain N‐acetylneuraminic acid alleviates hydrocephalus‐induced neurological deficits
por: Wang, Zhangyang, et al.
Publicado: (2023)

TAT-HSP27 Peptide Improves Neurologic Deficits via Reducing Apoptosis After Experimental Subarachnoid Hemorrhage
por: Zhou, Xiao-yan, et al.
Publicado: (2022)

Dental Pulp Stem Cell-Derived Factors Alleviate Subarachnoid Hemorrhage-Induced Neuroinflammation and Ischemic Neurological Deficits
por: Chen, Te-Fu, et al.
Publicado: (2019)

Phagocytosis of Gut Bacteria by Entamoeba histolytica
por: Iyer, Lakshmi Rani, et al.
Publicado: (2019)

Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis
por: Noda, Mariko, et al.
Publicado: (2012)

MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons
por: Fuller, Abby D., et al.
Publicado: (2008)

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
por: Sierra, Amanda, et al.
Publicado: (2013)

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
por: Zhao, Lian, et al.
Publicado: (2015)

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders
por: Nadjar, Agnes, et al.
Publicado: (2017)

Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets
por: Nizami, Sohaib, et al.
Publicado: (2019)

Microglial Phagocytosis—Rational but Challenging Therapeutic Target in Multiple Sclerosis
por: Pinto, Maria V., et al.
Publicado: (2020)

Central nervous system diseases related to pathological microglial phagocytosis
por: Wang, Ke, et al.
Publicado: (2021)

Metabolic regulation of microglial phagocytosis: Implications for Alzheimer's disease therapeutics
por: Lepiarz-Raba, Izabela, et al.
Publicado: (2023)

Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response
por: Cai, Qing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7t0hrgg3dj6vk8sor1hkrqo4b2