ORP2 couples LDL‐cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P(2) exchange

Low‐density lipoprotein (LDL)‐cholesterol delivery from late endosomes to the plasma membrane regulates focal adhesion dynamics and cell migration, but the mechanisms controlling it are poorly characterized. Here, we employed auxin‐inducible rapid degradation of oxysterol‐binding protein‐related pro...

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Detalles Bibliográficos
Autores principales: Takahashi, Kohta, Kanerva, Kristiina, Vanharanta, Lauri, Almeida‐Souza, Leonardo, Lietha, Daniel, Olkkonen, Vesa M, Ikonen, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281050/
https://www.ncbi.nlm.nih.gov/pubmed/34124795
http://dx.doi.org/10.15252/embj.2020106871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281050/
https://www.ncbi.nlm.nih.gov/pubmed/34124795
http://dx.doi.org/10.15252/embj.2020106871

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