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Purinergic Signaling in the Pathophysiology and Treatment of Huntington’s Disease

Huntington’s disease (HD) is a devastating, progressive, and fatal neurodegenerative disorder inherited in an autosomal dominant manner. This condition is characterized by motor dysfunction (chorea in the early stage, followed by bradykinesia, dystonia, and motor incoordination in the late stage), p...

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Detalles Bibliográficos
Autores principales: Wiprich, Melissa Talita, Bonan, Carla Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281137/
https://www.ncbi.nlm.nih.gov/pubmed/34276284
http://dx.doi.org/10.3389/fnins.2021.657338