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Selective Overexpression of Collybistin in Mouse Hippocampal Pyramidal Cells Enhances GABAergic Neurotransmission and Protects against PTZ-Induced Seizures
Collybistin (CB) is a rho guanine exchange factor found at GABAergic and glycinergic postsynapses that interacts with the inhibitory scaffold protein, gephyrin, and induces accumulation of gephyrin and GABA type-A receptors (GABA(A)Rs) to the postsynapse. We have previously reported that the isoform...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Society for Neuroscience
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281261/ https://www.ncbi.nlm.nih.gov/pubmed/34083383 http://dx.doi.org/10.1523/ENEURO.0561-20.2021 |