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Selective Overexpression of Collybistin in Mouse Hippocampal Pyramidal Cells Enhances GABAergic Neurotransmission and Protects against PTZ-Induced Seizures

Collybistin (CB) is a rho guanine exchange factor found at GABAergic and glycinergic postsynapses that interacts with the inhibitory scaffold protein, gephyrin, and induces accumulation of gephyrin and GABA type-A receptors (GABA(A)Rs) to the postsynapse. We have previously reported that the isoform...

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Detalles Bibliográficos
Autores principales: George, Shanu, James, Shaun, De Blas, Angel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281261/
https://www.ncbi.nlm.nih.gov/pubmed/34083383
http://dx.doi.org/10.1523/ENEURO.0561-20.2021

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