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Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a heterogeneous cancer. Better knowledge of molecular and cellular intra-tumor heterogeneity throughout the thoracic cavity is required to develop efficient therapies. This study focuses on molecular intra-tumor heterogeneity using the largest seri...

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Detalles Bibliográficos
Autores principales: Meiller, Clément, Montagne, François, Hirsch, Theo Z., Caruso, Stefano, de Wolf, Julien, Bayard, Quentin, Assié, Jean-Baptiste, Meunier, Léa, Blum, Yuna, Quetel, Lisa, Gibault, Laure, Pintilie, Ecaterina, Badoual, Cécile, Humez, Sarah, Galateau-Sallé, Françoise, Copin, Marie-Christine, Letouzé, Eric, Scherpereel, Arnaud, Zucman-Rossi, Jessica, Le Pimpec-Barthes, Françoise, Jaurand, Marie-Claude, Jean, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281651/
https://www.ncbi.nlm.nih.gov/pubmed/34261524
http://dx.doi.org/10.1186/s13073-021-00931-w