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Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia

BACKGROUND: Microglia are active modulators of Alzheimer’s disease but their role in relation to amyloid plaques and synaptic changes due to rising amyloid beta is unclear. We add novel findings concerning these relationships and investigate which of our previously reported results from transgenic m...

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Detalles Bibliográficos
Autores principales:	Benitez, Diana P., Jiang, Shenyi, Wood, Jack, Wang, Rui, Hall, Chloe M., Peerboom, Carlijn, Wong, Natalie, Stringer, Katie M., Vitanova, Karina S., Smith, Victoria C., Joshi, Dhaval, Saito, Takashi, Saido, Takaomi C., Hardy, John, Hanrieder, Jörg, De Strooper, Bart, Salih, Dervis A., Tripathi, Takshashila, Edwards, Frances A., Cummings, Damian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281661/ https://www.ncbi.nlm.nih.gov/pubmed/34266459 http://dx.doi.org/10.1186/s13024-021-00457-0

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