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Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study
BACKGROUND: In Uganda, the incidence and determinants of perinatal death in obstructed labour are not well documented. We determined the incidence and determinants of perinatal mortality among women with obstructed labour in Eastern Uganda. METHODS: Between July 2018 and September 2019, 584 with obs...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281707/ https://www.ncbi.nlm.nih.gov/pubmed/34266492 http://dx.doi.org/10.1186/s40748-021-00133-7 |
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author | Musaba, Milton W. Ndeezi, Grace Barageine, Justus K. Weeks, Andrew D. Wandabwa, Julius N. Mukunya, David Waako, Paul Odongkara, Beatrice Arach, Agnes Tulya-muhika Mugabe, Kenneth Kasede Napyo, Agnes Nankabirwa, Victoria Tumwine, James K. |
author_facet | Musaba, Milton W. Ndeezi, Grace Barageine, Justus K. Weeks, Andrew D. Wandabwa, Julius N. Mukunya, David Waako, Paul Odongkara, Beatrice Arach, Agnes Tulya-muhika Mugabe, Kenneth Kasede Napyo, Agnes Nankabirwa, Victoria Tumwine, James K. |
author_sort | Musaba, Milton W. |
collection | PubMed |
description | BACKGROUND: In Uganda, the incidence and determinants of perinatal death in obstructed labour are not well documented. We determined the incidence and determinants of perinatal mortality among women with obstructed labour in Eastern Uganda. METHODS: Between July 2018 and September 2019, 584 with obstructed labour were recruited and followed up to the 7th day postnatal. Information on maternal characteristics, obstetric factors and laboratory parameters was collected. Each patient received the standard perioperative care. We used a generalized linear model for the Poisson family, with a log link and robust variance estimation to determine the association between the exposure variables and perinatal death. RESULTS: Of the 623 women diagnosed with obstructed labour, 584 met the eligibility criteria. There were 24 fresh still births (FSB) and 32 early neonatal deaths (ENND) giving an FSB rate of 43.8 (95% CI 28.3–64.4) deaths per 1000 total births; early neonatal death rate of 58.4 (95% CI 40.3–81.4) deaths per 1000 and an overall perinatal mortality rate of 102.2 (95% CI 79.4–130.6) deaths in the first 7 days of life. A mother being referred in active labour adjusted risk ratio of 2.84 (95% CI: 1.35–5.96) and having high blood lactate levels at recruitment adjusted risk ratio 2.71 (95% CI: 1.26–4.24) were the determinants of perinatal deaths. CONCLUSIONS: The incidence of perinatal death was four times the regional and national average. Babies to women referred in active labour and those with high maternal blood lactate were more likely to die. |
format | Online Article Text |
id | pubmed-8281707 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82817072021-07-16 Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study Musaba, Milton W. Ndeezi, Grace Barageine, Justus K. Weeks, Andrew D. Wandabwa, Julius N. Mukunya, David Waako, Paul Odongkara, Beatrice Arach, Agnes Tulya-muhika Mugabe, Kenneth Kasede Napyo, Agnes Nankabirwa, Victoria Tumwine, James K. Matern Health Neonatol Perinatol Research Article BACKGROUND: In Uganda, the incidence and determinants of perinatal death in obstructed labour are not well documented. We determined the incidence and determinants of perinatal mortality among women with obstructed labour in Eastern Uganda. METHODS: Between July 2018 and September 2019, 584 with obstructed labour were recruited and followed up to the 7th day postnatal. Information on maternal characteristics, obstetric factors and laboratory parameters was collected. Each patient received the standard perioperative care. We used a generalized linear model for the Poisson family, with a log link and robust variance estimation to determine the association between the exposure variables and perinatal death. RESULTS: Of the 623 women diagnosed with obstructed labour, 584 met the eligibility criteria. There were 24 fresh still births (FSB) and 32 early neonatal deaths (ENND) giving an FSB rate of 43.8 (95% CI 28.3–64.4) deaths per 1000 total births; early neonatal death rate of 58.4 (95% CI 40.3–81.4) deaths per 1000 and an overall perinatal mortality rate of 102.2 (95% CI 79.4–130.6) deaths in the first 7 days of life. A mother being referred in active labour adjusted risk ratio of 2.84 (95% CI: 1.35–5.96) and having high blood lactate levels at recruitment adjusted risk ratio 2.71 (95% CI: 1.26–4.24) were the determinants of perinatal deaths. CONCLUSIONS: The incidence of perinatal death was four times the regional and national average. Babies to women referred in active labour and those with high maternal blood lactate were more likely to die. BioMed Central 2021-07-15 /pmc/articles/PMC8281707/ /pubmed/34266492 http://dx.doi.org/10.1186/s40748-021-00133-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Musaba, Milton W. Ndeezi, Grace Barageine, Justus K. Weeks, Andrew D. Wandabwa, Julius N. Mukunya, David Waako, Paul Odongkara, Beatrice Arach, Agnes Tulya-muhika Mugabe, Kenneth Kasede Napyo, Agnes Nankabirwa, Victoria Tumwine, James K. Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title | Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title_full | Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title_fullStr | Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title_full_unstemmed | Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title_short | Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study |
title_sort | incidence and determinants of perinatal mortality among women with obstructed labour in eastern uganda: a prospective cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281707/ https://www.ncbi.nlm.nih.gov/pubmed/34266492 http://dx.doi.org/10.1186/s40748-021-00133-7 |
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