Haplotype-resolved germline and somatic alterations in renal medullary carcinomas

BACKGROUND: Renal medullary carcinomas (RMCs) are rare kidney cancers that occur in adolescents and young adults of African ancestry. Although RMC is associated with the sickle cell trait and somatic loss of the tumor suppressor, SMARCB1, the ancestral origins of RMC remain unknown. Further, charact...

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Detalles Bibliográficos
Autores principales: Tan, Kar-Tong, Kim, Hyunji, Carrot-Zhang, Jian, Zhang, Yuxiang, Kim, Won Jun, Kugener, Guillaume, Wala, Jeremiah A., Howard, Thomas P., Chi, Yueh-Yun, Beroukhim, Rameen, Li, Heng, Ha, Gavin, Alper, Seth L., Perlman, Elizabeth J., Mullen, Elizabeth A., Hahn, William C., Meyerson, Matthew, Hong, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281718/
https://www.ncbi.nlm.nih.gov/pubmed/34261517
http://dx.doi.org/10.1186/s13073-021-00929-4

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