A Prolonged Neurological Presentation of Legionnaire's Disease

Legionnaire’s disease is an uncommon pneumonic disease that can carry a mortality rate up to 20%. It commonly presents as an atypical lower respiratory illness. However, it is important to be mindful of the various extra-pulmonic presentations of the infection. Here, we present a case of a 51-year-old female who presented to the emergency department with lethargy, slurred speech, and confusion. Legionella has been reported to present with neurological symptoms but it is not a common occurrence in each hospitalization. These neurological symptoms often lead to an extensive workup and the complexity of the diagnostic workup can significantly influence patient outcome. However, it is crucial that physicians follow a systemic approach to establish a diagnosis in an expedited manner. This case emphasizes the importance of key objective evidence of legionella that can help guide a physician’s diagnostic approach.