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Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu

INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal...

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Autores principales: Bahl, Saransh, Dogra, Sandeep, Bahl, Rakesh, Sachdeva, Amit, Mahajan, Bella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281848/
https://www.ncbi.nlm.nih.gov/pubmed/34321745
http://dx.doi.org/10.4103/ijcm.IJCM_347_20
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author Bahl, Saransh
Dogra, Sandeep
Bahl, Rakesh
Sachdeva, Amit
Mahajan, Bella
author_facet Bahl, Saransh
Dogra, Sandeep
Bahl, Rakesh
Sachdeva, Amit
Mahajan, Bella
author_sort Bahl, Saransh
collection PubMed
description INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal titers among healthy individuals in a defined population. OBJECTIVES: To determine the baseline Widal titers among apparently healthy urban population of district Jammu (J&K). MATERIALS AND METHODS: 302 individuals in the age group of 18–50 years were recruited. A pretested questionnaire was used to collect demographic and clinical details. The Widal testing was done using commercial Salmonella antigen kit. RESULTS: A total of 302 samples were screened by Widal test. 138 samples (45.69%) were reactive for TO antigen and 64 (21.19%) tested reactive for TH antigen, 3 (0.01%) samples showed agglutination for AH antigen and 3 (0.01%) were positive for BH antigen. Majority of seropositive samples were in dilutions of 1:40 for both TO and TH antigens. CONCLUSIONS: Hence, next higher dilutions showing positivity for both TO and TH antigens, i.e., ≥1:80 may be considered diagnostic for enteric fever in the urban population of Jammu district.
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spelling pubmed-82818482021-07-27 Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu Bahl, Saransh Dogra, Sandeep Bahl, Rakesh Sachdeva, Amit Mahajan, Bella Indian J Community Med Short Communication INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal titers among healthy individuals in a defined population. OBJECTIVES: To determine the baseline Widal titers among apparently healthy urban population of district Jammu (J&K). MATERIALS AND METHODS: 302 individuals in the age group of 18–50 years were recruited. A pretested questionnaire was used to collect demographic and clinical details. The Widal testing was done using commercial Salmonella antigen kit. RESULTS: A total of 302 samples were screened by Widal test. 138 samples (45.69%) were reactive for TO antigen and 64 (21.19%) tested reactive for TH antigen, 3 (0.01%) samples showed agglutination for AH antigen and 3 (0.01%) were positive for BH antigen. Majority of seropositive samples were in dilutions of 1:40 for both TO and TH antigens. CONCLUSIONS: Hence, next higher dilutions showing positivity for both TO and TH antigens, i.e., ≥1:80 may be considered diagnostic for enteric fever in the urban population of Jammu district. Wolters Kluwer - Medknow 2021 2021-05-29 /pmc/articles/PMC8281848/ /pubmed/34321745 http://dx.doi.org/10.4103/ijcm.IJCM_347_20 Text en Copyright: © 2021 Indian Journal of Community Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Bahl, Saransh
Dogra, Sandeep
Bahl, Rakesh
Sachdeva, Amit
Mahajan, Bella
Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title_full Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title_fullStr Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title_full_unstemmed Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title_short Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
title_sort estimation of baseline widal antibody titers among apparently healthy urban population of district jammu
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281848/
https://www.ncbi.nlm.nih.gov/pubmed/34321745
http://dx.doi.org/10.4103/ijcm.IJCM_347_20
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