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Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu
INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281848/ https://www.ncbi.nlm.nih.gov/pubmed/34321745 http://dx.doi.org/10.4103/ijcm.IJCM_347_20 |
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author | Bahl, Saransh Dogra, Sandeep Bahl, Rakesh Sachdeva, Amit Mahajan, Bella |
author_facet | Bahl, Saransh Dogra, Sandeep Bahl, Rakesh Sachdeva, Amit Mahajan, Bella |
author_sort | Bahl, Saransh |
collection | PubMed |
description | INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal titers among healthy individuals in a defined population. OBJECTIVES: To determine the baseline Widal titers among apparently healthy urban population of district Jammu (J&K). MATERIALS AND METHODS: 302 individuals in the age group of 18–50 years were recruited. A pretested questionnaire was used to collect demographic and clinical details. The Widal testing was done using commercial Salmonella antigen kit. RESULTS: A total of 302 samples were screened by Widal test. 138 samples (45.69%) were reactive for TO antigen and 64 (21.19%) tested reactive for TH antigen, 3 (0.01%) samples showed agglutination for AH antigen and 3 (0.01%) were positive for BH antigen. Majority of seropositive samples were in dilutions of 1:40 for both TO and TH antigens. CONCLUSIONS: Hence, next higher dilutions showing positivity for both TO and TH antigens, i.e., ≥1:80 may be considered diagnostic for enteric fever in the urban population of Jammu district. |
format | Online Article Text |
id | pubmed-8281848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-82818482021-07-27 Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu Bahl, Saransh Dogra, Sandeep Bahl, Rakesh Sachdeva, Amit Mahajan, Bella Indian J Community Med Short Communication INTRODUCTION: Definitive diagnosis of Enteric fever is by blood culture for Salmonella enterica serotype Typhi, Paratyphi A, and Paratyphi B which takes long turnaround time and is costly, whereas Widal test is simple, rapid, and cost-effective test whose interpretation depends on the baseline Widal titers among healthy individuals in a defined population. OBJECTIVES: To determine the baseline Widal titers among apparently healthy urban population of district Jammu (J&K). MATERIALS AND METHODS: 302 individuals in the age group of 18–50 years were recruited. A pretested questionnaire was used to collect demographic and clinical details. The Widal testing was done using commercial Salmonella antigen kit. RESULTS: A total of 302 samples were screened by Widal test. 138 samples (45.69%) were reactive for TO antigen and 64 (21.19%) tested reactive for TH antigen, 3 (0.01%) samples showed agglutination for AH antigen and 3 (0.01%) were positive for BH antigen. Majority of seropositive samples were in dilutions of 1:40 for both TO and TH antigens. CONCLUSIONS: Hence, next higher dilutions showing positivity for both TO and TH antigens, i.e., ≥1:80 may be considered diagnostic for enteric fever in the urban population of Jammu district. Wolters Kluwer - Medknow 2021 2021-05-29 /pmc/articles/PMC8281848/ /pubmed/34321745 http://dx.doi.org/10.4103/ijcm.IJCM_347_20 Text en Copyright: © 2021 Indian Journal of Community Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Bahl, Saransh Dogra, Sandeep Bahl, Rakesh Sachdeva, Amit Mahajan, Bella Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title | Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title_full | Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title_fullStr | Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title_full_unstemmed | Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title_short | Estimation of Baseline Widal Antibody Titers among Apparently Healthy Urban Population of District Jammu |
title_sort | estimation of baseline widal antibody titers among apparently healthy urban population of district jammu |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281848/ https://www.ncbi.nlm.nih.gov/pubmed/34321745 http://dx.doi.org/10.4103/ijcm.IJCM_347_20 |
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