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Human Beta-Defensin 2 and 3 Inhibit HIV-1 Replication in Macrophages
Human beta-defensins (hBDs) are broad-spectrum antimicrobial peptides, secreted by epithelial cells of the skin and mucosae, and astrocytes, which we and others have shown to inhibit HIV-1 in primary CD4(+) T cells. Although loss of CD4(+) T cells contributes to mucosal immune dysfunction, macrophag...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281893/ https://www.ncbi.nlm.nih.gov/pubmed/34277460 http://dx.doi.org/10.3389/fcimb.2021.535352 |