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eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants
While advancements in genome sequencing have identified millions of somatic mutations in cancer, their functional impact is poorly understood. We previously developed the expression-based variant impact phenotyping (eVIP) method to use gene expression data to characterize the function of gene varian...
Autores principales: | Thornton, Alexis M., Fang, Lishan, Lo, April, McSharry, Maria, Haan, David, O’Brien, Casey, Berger, Alice H., Giannakis, Marios, Brooks, Angela N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281988/ https://www.ncbi.nlm.nih.gov/pubmed/34214079 http://dx.doi.org/10.1371/journal.pcbi.1009132 |
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